Kaletra(Lopinavir/Ritonavir)- HIV Medication & Treatment

Kaletra (Lopinavir /Ritonavir) - HIV Treatment


Treating HIV infection. It is used along with other medicines for HIV. Kaletra (Lopinavir /Ritonavir) is a combination of 2 HIV protease inhibitors. It works by stopping the HIV virus from multiplying.

Mechanism of action:

Lopinavir inhibits the HIV viral protease enzyme. This prevents cleavage of the gag-pol polyprotein and, therefore, improper viral assembly results. This subsequently results in non-infectious, immature viral particles
Ritonavir inhibits the HIV viral proteinase enzyme which prevents cleavage of the gag-pol polyprotein, resulting in noninfectious, immature viral particles.

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